Ondansetron (Brand Name(s): Zofran)

This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body’s natural substances (serotonin) that causes vomiting.


  • Blocks the actions of chemicals in the body that can trigger nausea and vomiting
  • Can be used after recovering from surgery, during chemotherapy, or radiation
  • Zofran is not recommended during pregnancy

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